List of non-standard abbreviations: ACN acetonitrile CYP cytochrome P450 DCM dichloromethane EC electrochemistry ESI-MS electrospray ionization mass spectrometry

Non-standard abbreviations used: CYP: cytochrome P450; HT: hexahistidine-tagged; ES/LC-MS: electrospray ionization/liquid chromatography mass spectrometry; PMSF: phenylmethylsulfonyl fluoride; CHAPS: 3-[(3-cholamidopropyl)dimethyl-ammonio]-1-propanesulfonate; EDDP: 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine; TFA: trifluoroacetic acid

Electrospray ionization mass spectrometry of a novel family of complexes in which various nitroso compounds are stabilized via coordination to [IrCl5]2-.

Electrospray ionization mass spectrometry (ESI-MS) and tandem mass spectrometry (ESI-MS/MS) data of a unique family of complexes of nitroso compounds coordinated to pentachloroiridate(III), [Cl5IrN(O)XR]2- (X=NH, S, CH and R=alkyl, aryl) are presented. These novel complexes are obtained by nucleophilic attack of primary amines, thiols. and alkenes to the coordinated nitrosyl. Despite their labi...

Quantification of Melittin in Iranian Honey Bee (Apis mellifera meda) Venom by Liquid Chromatography-electrospray Ionization-ion Trap Tandem Mass Spectrometry (LC-ESI-IT-MS/MS)

The current research aimed to quantify melittin (MEL) in Iranian honey bee (Apis mellifera meda) venom. To this end, a liquid chromatography-electrospray ionization-ion trap tandem mass spectrometry (LC-ESI-IT-MS/MS) approach was employed. Melittin is the main toxic peptide of honey bee venom with various biological and pharmacological activities. It was extracted with...

Application of on-line electrochemistry/electrospray/tandem mass spectrometry to a quantification method for the antipsychotic drug zotepine in human serum.

A simple, rapid, and sensitive on-line liquid chromatographic electrochemistry/electrospray/tandem mass spectrometry (LC-EC/ESI-MS/MS) method for the determination of zotepine in human serum was developed using a new generated-electrochemically fragment ion, and was validated. A recent novel technique of LC-EC/ESI-MS/MS that combines LC-MS/MS and the on-line EC reaction is potentially applicabl...

Mass spectrometric methods for monitoring redox processes in electrochemical cells

Electrochemistry (EC) is a mature scientific discipline aimed to study the movement of electrons in an oxidation-reduction reaction. EC covers techniques that use a measurement of potential, charge, or current to determine the concentration or the chemical reactivity of analytes. The electrical signal is directly converted into chemical information. For in-depth characterization of complex elec...